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Degenerative Disk Disease Market: Analysis of Epidemiology, Pipeline Therapies, and Key Companies Working in the Market

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Degenerative Disk Disease Market: Analysis of Epidemiology, Pipeline Therapies, and Key Companies Working in the Market

November 14
23:04 2022
 Degenerative Disk Disease Market: Analysis of Epidemiology, Pipeline Therapies, and Key Companies Working in the Market
DelveInsight Business Research LLP
DelveInsight’s “Degenerative Disc Disease (DDD) Market Insights, Epidemiology, and Market Forecast-2032” report delivers an in-depth understanding of the Degenerative Disc Disease (DDD), historical and forecasted epidemiology as well as the Degenerative Disc Disease (DDD) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

DelveInsight’s Degenerative Disc Disease (DDD) Market Insights, Epidemiology, and Market Forecast-2032″ report delivers an in-depth understanding of the Degenerative Disc Disease (DDD), historical and forecasted epidemiology as well as the Degenerative Disc Disease (DDD) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

 

The Degenerative Disc Disease (DDD) market report provides current treatment practices, emerging drugs, Degenerative Disc Disease (DDD) market share of the individual therapies, current and forecasted Degenerative Disc Disease (DDD) market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current Degenerative Disc Disease (DDD) treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the Degenerative Disc Disease (DDD) market.

Some of the key facts of the  Degenerative Disk Disease Report:

  • As per the study conducted by Brinjikji et al. (2014), the prevalence of disk degeneration in asymptomatic individuals increased from 37% of 20-year-old individuals to 96% of 80-year-old individuals. Disk bulge prevalence increased from 30% of those 20 years of age to 84% of those 80 years of age. Disk protrusion prevalence increased from 29% of those 20 years of age to 43% of those 80 years of age. The prevalence of annular fissure increased from 19% of those 20 years of age to 29% of those 80 years of age.

  • According to a study conducted by Tao et al. (2020), commonly, 53.9% (n = 852; 386 males, 466 females; mean age = 52.3 ± 16.6 years) of all the subjects presented with radiographic cervical disc degeneration, and the prevalence of disc degeneration was not significantly different between males and females (53.4 vs. 54.3%). 36.8% of the subjects had Grade 1 (mild degeneration) disc degeneration, 13.7% had Grade 2 (moderate degeneration) and 3.4% had Grade 3 (severe degeneration).

Key benefits of the report:

  • The report covers a descriptive overview of Degenerative Disc Disease (DDD), explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies

  • Comprehensive insight has been provided into the Degenerative Disc Disease (DDD) epidemiology and treatment in the 7MM

  • Additionally, an all-inclusive account of both the current and emerging therapies for Degenerative Disc Disease (DDD) is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape

  • A detailed review of the Degenerative Disc Disease (DDD) market; historical and forecasted is included in the report, covering drug outreach in the 7MM

  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Degenerative Disc Disease (DDD) market

Got queries? Click here to learn more about  Degenerative Disk Disease Insights 

Degenerative Disk Disease s Overview

Degenerative Disk Disease (DDD) is a common disorder that is characterized by progressive degeneration of the intervertebral disc; rendering them deformed and mechanically dysfunctional. It is a catchall phrase for a number of structural changes in the spine, such as loss of disc height, disc bulges, hydration, and impingement of nerves in the spine, among others.

The resultant loss of structural and functional integrity of the spine can lead to lumbar and/or cervical pain syndromes; the discs are unable to fulfill their primary functions of cushioning and providing mobility between the vertebrae; consequently, DDD has been reported as a leading cause of low back pain. Disc degeneration, although in many cases asymptomatic, is also associated with sciatica and disc herniation or prolapse. 

DDD can be diagnosed through imaging tests like X-rays, a magnetic resonance imaging scan (MRI), or computed tomography (CT) scan which can get a better look at the discs and bony structure.DDD can often be managed conservatively through physical therapy, chiropractic manipulative therapy, osteopathic manipulation, anti-inflammatory medications, such as non-steroidal anti-inflammatory drugs (NSAIDs), and/or spinal injections, epidural steroid injections that can provide pain relief. If these more moderate approaches fail to alleviate symptoms, surgery may be necessary

 Degenerative Disk Disease Epidemiological Insights

  • As per the study conducted by Teraguchi et al. (2014), the prevalence of intervertebral disc degeneration (DD) over the entire spine was 71% in men and 77% in women aged 90% in both men and women aged >50 years. The prevalence of an intervertebral space with DD was highest at C5/6 (men: 51.5%, women: 46%), T6/7 (men: 32.4%, women: 37.7%), and L4/5 (men: 69.1%, women: 75.8%). 

  • As per the data published on the International Society for Pediatric Neurosurgery (ESPN), DDD is more prevalent than previously suspected, with 26% of asymptomatic children

  • As per the study conducted by Bruin et al. (2018), degenerative changes were found in 456/648 patients (70.4%). Degenerated discs and Schmorls nodes had the highest prevalence and were present in 278/648 patients (42.9%) and 238/648 patients (36.7%), respectively. More male patients had degenerative changes (226/303 (74.6%) males vs 230/345 (66.7%) females, and this difference is almost completely explained by the higher prevalence of Schmorls nodes (136/303 (44.9%) males and 102/345 (29.6%) females). The prevalence of other degenerative changes on both MRI and radiograph were comparable in both genders. On radiographs, degenerative changes were found in 191/648 patients (29.5%). Male and female patients were equally represented; 92/303 men (30.4%) and 99/345 women (28.7%). Prevalence of degeneration was lower on radiographs compared with MRI; loss of disc height was most prevalent on the radiographs and was found in 153/648 patients (23.6%).

 

 Degenerative Disk Disease Epidemiological Segmentation 

 

  • Total Degenerative Disk Disease prevelant cases 

  • Total Degenerative Disk Disease diagnosed cases 

  • Total Degenerative Disk Disease treated cases 

  • Total Degenerative Disc Disease age-specific cases 

  • Total Degenerative Disc Disease severity-specific cases 

 

Degenerative Disk Disease  Outlook

The Degenerative Disc Disease (DDD) market outlook of the report helps to build a detailed comprehension of the historic, current, and forecasted Degenerative Disc Disease (DDD) market trends by analyzing the impact of current Degenerative Disc Disease (DDD) therapies on the market, unmet needs, drivers and barriers, and demand for better technology.

 

This segment gives a thorough detail of the Degenerative Disc Disease (DDD) market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Degenerative Disc Disease (DDD) market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

 

According to DelveInsight, the Degenerative Disc Disease (DDD) market in 7MM is expected to witness a major change in the study period 2019-2032.

 

Learn more by requesting for sample @ Degenerative Disk Disease MarketLandscape

 Degenerative Disk Disease Key Companies

  •  Mesoblast/ Gruenthal

  •  Stayble Therapeutics

  •  Kuros Biosciences

  • And many others 

 

 Degenerative Disk Disease Therapies

 

  • Rexlemestrocel

  • STA363

  • Fibrin-PTH (KUR-113)

  • And many more 

 

Market Drivers 

 

  • Rich emerging pipeline

  • Increasing Prevalence of DDD

  • Advances in disease understanding

 

  Market Barriers

 

  • Impact on quality of life of the patient

  • Failure to recognize the condition delays commencement of more appropriate care

 

Table of Contents

 

  1. Key Insights 

  2. Report Introduction 

  3. Executive Summary of  Degenerative Disk Disease

  4. Disease Background and Overview

  5. Epidemiology and patient population 

  6. Degenerative Disk Disease, Emerging Therapies

  7.  Degenerative Disk Disease, Market Outlook

  8. Market Access and Reimbursement of Therapies

  9. Market Drivers

  10. Market Barriers 

  11. Appendix

  12. Degenerative Disk Disease, Report Methodology

  13. DelveInsight Capabilities

  14.  Disclaimer

  15. About DelveInsight

Click here to read more about  Degenerative Disk Disease ,Market Insights

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